Research and Development

Independent Vascular Services performs many research and development projects, most in the main unit at the University Hospital of South Manchester itself, or in conjunction with the University of Manchester and also take part in multicentre studies both nationally and internationally. We have a multidisciplinary team of vascular scientists, medical physicists, doctors and nurses. We work closely with industry experts from the field of medicine and medical imaging to continually improve and innovate new diagnostic and minimally invasive vascular technologies.

At IVS we strive to lead the way in vascular research, currently we are involved in a number of exciting research projects using our cutting edge 3D technology. This technology has the potential to replace CT angiography for a number of our vascular patients.

Our first published study using 3D, was a pilot study evaluating 3D with contrast enhanced ultrasound to identify endoleaks, following endovascular aneurysm repair. This was a pilot study and concluded that 3D CEUS may be more sensitive than CT angiography and 2D contrast enhanced ultrasound.

Future studies, include using 3D ultrasound to measure the volume of the intima in the temporal artery to discover if this a valid method of diagnosing temporal arteritis, this will be a beneficial study for patients as currently diagnosis is made via a biopsy of the temporal artery. We are also measuring the volume of plaque in the internal carotid artery to see if this can help identify which patients are at risk of stroke from the plaque in the artery and should therefore have urgent surgery.

As well as research using 3D ultrasound, at IVS we are currently supporting the CHAMPioN study and the APEX study.

The CHAMPion study is investigating patient with cancer and assessing them for clots in the legs (deep vein thrombosis). There is some evidence that patients who develop deep vein thrombosis and pulmonary embolisms during their cancer treatment have more aggressive cancers. If we can identify cancer patients with more aggressive cancers (by using abnormalities of clotting as a marker), or patients at risk of thrombosis, we will be able to tailor their treatment more precisely.

The APEX study is an international multi centred randomised control study, that involves detailed scans of the lower limb venous system. This study is looking at alternative drug to Clexane for preventing DVT and treating DVT.

Details of IVS’s current service developments can be found below.


IVS Diagnostic

Can save 17% to 34% of the cost of setting up and running a vascular laboratory

Reduces capital expenditure

Lowers staff and administration costs

95% of inpatients investigated the same day




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0161 998 2626

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